Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis
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چکیده
منابع مشابه
3-nitrotyrosine levels in dichlorvos-induced neurotoxicity.
The aim of this study was to evaluate dichlorvos toxicity in terms of nitro-oxidative stress by determining 3-nitrotyrosine (3-NT) levels in the fore, mid, and hindbrain regions in acutely exposed rats. Male Sprague- Dawley rats were randomly allocated to three groups of eight. Group 1 was administered a single intraperitoneal dichlorvos dose of 1.8 mg kg ⁻¹(0.1xLD₅₀) and group 2 a dose of 9 mg...
متن کاملToxicity assessment of Erythrophleum ivorense and Parquetina nigrescens
Erythrophleum ivorense and Parquetina nigrescens are found growing in tropical regions and they are used in African traditional medicine to treat various ailments including wounds, boils and anaemic conditions. Some species of plant in the Erythrophleum genus are also known to be poisonous and toxic to several livestock. However, there is no information on the toxicity of E. ivorense and P. nig...
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BACKGROUND The plant, Parquetina nigrescens is used in folklore medicine to treat diabetes mellitus and its complications in several parts of West Africa. OBJECTIVE To determine the effect of Parquetina nigrescens extract on fasting blood glucose in alloxan-induced diabetic rats. METHODS The blood glucose levels, complete blood count, erythrocyte indices and osmotic fragility, body and orga...
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A diet rich in polyphenols has previously been shown to be associated with a lower risk for cardiovascular disease. Specifically, inhibition of platelet hyperactivation by polyphenols decreases platelet-dependent thrombosis, reducing the risk for cardiovascular disease. However, whether polyphenols in Salvia miltiorrhiza Bunge (SMB) affect platelet functions has not been clearly determined. Her...
متن کاملImmunohistochemical and Electron Microscopic Study of the Inhibitory Effects of Olive Oil Polyphenol on Dexamethasone-Induced Apoptosis
Background: There is accumulating evidence that a polyphenol present in olive oil, oleuropein, has antioxidant, anti-inflammatory and anti-apoptotic effects. This study aimed at determining the anti-apoptotic effect of Oleuropein (Ole) on dexamethasone-induced apoptosis of mouse thymocytes. Method: Mice ...
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ژورنال
عنوان ژورنال: Journal of Ayurveda and Integrative Medicine
سال: 2017
ISSN: 0975-9476
DOI: 10.1016/j.jaim.2016.09.002